重点:ARDS输注干扰素β-1a对ARDS病死率及非机械通气时间的效果
1.脓*症与医保受益人
2.儿科社区获得性休克患儿远期病死率及生活质量相关影响因素
3.ICU成人急性/急转慢肝衰治疗指南
4.全球ECMO教育及教育日程的立场文件
5.荟萃分析:持续静点肾上腺素对重症患者生存率的影响
6.人性化的重症医学
7.ICU谵妄持续时间与严重度的生物标志物
8.监测呼吸驱动及吸气努力的技术
9.ICU的膈肌功能监测
10.膈肌保护何为目标
11.基于计算机临床决策系统的膈肌保护实施
12.中心静脉插管荟萃分析的前百篇文献
13.新冠病*肺炎的重症监护
14.欧洲之声:重症医师应对严重新冠病*感染的考虑及治疗意见
15.急性心梗并心源性休克患者血管内微轴左室辅助装置与IABP的院内病死率与大出血的比较
16.支气管肺泡灌洗液醋酸维生素E与电子烟相关性肺损伤相关
17.系统评价:成人心源性休克近红外光谱仪
18.综述:ECMO与右心衰
19.与脓*症休克中去甲肾剂量、心动过速与疾病结局
20.PulmCrit推荐的SCCM年会最佳20篇摘要
重点:
ARDS输注干扰素β-1a对ARDS病死率及非机械通气时间的效果EffectofIntravenousInterferonβ-1aonDeathandDaysFreeFromMechanicalVentilationAmongPatientsWithModeratetoSevereAcuteRespiratoryDistressSyndromeARandomizedClinicalTrial
V.MarcoRanieri,
doi:10./jama..
ImportanceAcuterespiratorydistresssyndrome(ARDS)isassociatedwithhighmortality.Interferon(IFN)β-1amaypreventtheunderlyingeventofvascularleakage.
ObjectiveTodeterminetheefficacyandadverseeventsofIFN-β-1ainpatientswithmoderatetosevereARDS.
Design,Setting,andParticipantsMulticenter,randomized,double-blind,parallel-grouptrialconductedat74intensivecareunitsin8Europeancountries(December-December)thatincludedadultswithmoderatetosevereARDSaccordingtotheBerlindefinition.Theradiologicalandpartialpressureofoxygen,arterial(Pao2)/fractionofinspiredoxygen(Fio2)criteriaforARDShadtobemetwithina24-hourperiod,andtheadministrationofthefirstdoseofthestudydrughadtooccurwithin48hoursofthediagnosisofARDS.ThelastpatientvisitwasonMarch6,.
InterventionsPatientswererandomizedtoreceiveanintravenousinjectionof10μgofIFN-β-1a(patients)orplacebo(patients)oncedailyfor6days.
MainOut